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Polynucleotides

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What is Kiara Reju® Polynucleotides?

Kiara Reju® Polynucleotides are a cutting-edge injectable treatment, offered by Natural Aesthetics in Cape Town, designed to rejuvenate and improve overall skin quality. Unlike traditional cosmetic procedures, Kiara Reju® focuses on supporting skin health by using polynucleotides together with hyaluronic acid and niacinamide to help hydrate, repair, and enhance the skin’s natural regenerative processes. This innovative treatment can be used in various areas including the under-eye area, face, neck, and décolleté, where it helps restore vitality and reduce visible signs of ageing.

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How Does Kiara Reju® Polynucleotides Work?

Kiara Reju® injections work by delivering a high concentration of polynucleotides directly into the skin. These molecules support the skin’s natural regenerative processes and help improve overall skin quality.

Polynucleotides are naturally derived molecules used in regenerative aesthetic treatments to support the skin’s natural renewal processes. Kiara Reju® is commonly used to improve the appearance of dull, tired or ageing skin and can be incorporated into personalised treatment plans to support smoother-looking texture, improved elasticity and a fresher-looking complexion.

In combination with hyaluronic acid and niacinamide, Kiara Reju® helps improve hydration, support skin elasticity, and enhance the appearance of skin texture and radiance.

Why Choose Kiara Reju® Polynucleotides Over Other Treatments?

  • Over Dermal Fillers: While dermal fillers primarily add volume and contour, Kiara Reju® focuses on enhancing overall skin quality. It works to improve hydration, texture, and elasticity rather than addressing volume loss alone.

  • Over Skinboosters: While some injectable treatments focus primarily on hydration and glow, Kiara Reju® Polynucleotides offer a broader skin rejuvenation approach by supporting skin regeneration and overall skin quality. This makes it a valuable treatment for patients wanting improved texture, radiance, and skin vitality.

  • Over Biostimulators: Biostimulators, like Sculptra®, primarily focus on stimulating collagen production, providing volumising and lifting effects over time. Kiara Reju® Polynucleotides are designed to improve overall skin quality, hydration, and texture, making them a versatile option for patients wanting fresher, healthier-looking skin.

Discover Polynucleotides

Polynucleotides are an injectable bio-stimulator and advanced skin rejuvenation treatment used to improve the appearance of fine lines and wrinkles, support skin elasticity, and enhance overall skin quality. This treatment can help improve the appearance of dull, dehydrated or ageing skin and is commonly used to rejuvenate delicate areas such as the under-eye area, as well as the face, neck and décolleté.

Performed by our medical doctors, each treatment involves a series of microinjections of Kiara Reju® Polynucleotides into the skin. Depending on your treatment plan, this may include areas such as the under-eye area, face, neck or décolleté.

 
 

The skin around the eyes, as well as the face, neck and décolleté is constantly exposed to environmental stressors, sun exposure and repeated facial movements, which can contribute to visible signs of ageing such as fine lines, loss of elasticity and dull-looking skin.

Kiara Reju® contains a highly purified polynucleotide complex designed to support the skin’s natural regenerative processes. When introduced into the skin, polynucleotides help support skin renewal, hydration and overall skin quality.

Kiara Reju® supports skin rejuvenation through multiple mechanisms within the skin layers:

  • Effect on the dermal-epidermal layer
  • Effect on the vascular level
  • Effect on the deeper tissue level


Kiara Reju® – key characteristics of this advanced polynucleotide treatment:

  • Kiara Reju® contains a purified polynucleotide complex combined with hyaluronic acid and niacinamide
  • The carefully formulated structure supports effective distribution within the skin while helping to improve hydration, skin vitality and overall skin quality

It can take up to 3-4 days for the product to fully settle. During this period, you might experience swelling, tenderness, redness, bruising, itching, or notice small lumps or bumps in the treated area. Initially, there may also be asymmetry due to uneven swelling or the way the product settles. Typically, these conditions self-correct as the swelling subsides and the product integrates with your tissue.

  • Immediately after: You will have small lumps and bumps in the area that was treated – no need to worry though – these settle after a few days – the speed to which they disappear is dependent on your skin quality. You may experience mild tenderness, redness and swelling at the injection sites, which are normal and will resolve quickly. While rare, bruising may occur, which can be covered with concealer. Paracetamol can be taken for any tenderness or discomfort.
  • Ice Brick: Use an ice brick and gently press over the treated area for 15 minutes every hour in case of swelling.
  • Pressure & Touching: Avoid touching or massaging the treated area unless specifically instructed to do so. Avoid vigorous massage of the treated area for 48 hours.
  • Sleeping Position: There is no recommendation for how you sleep – sleeping on your side or your face does not impact the effectiveness of your treatment.
  • Postpone Exercise: Avoid engaging in exercise for 24 hours after your treatment. Physical activity can increase swelling and redness, hindering the healing process.
  • Stay Local: Long-haul flights must be avoided for 1 week post filler due to edema or swelling.
  • Delay Treatments & Procedures: Wait for at least two weeks before resuming any dental procedures, including dental cleanings and teeth whitening. During this period, also avoid surgeries or inoculations. Additionally, for at least two weeks after treatment, refrain from any form of hair removal, such as waxing, threading, laser, or IPL, as well as any skin or facial treatments.
  • No Makeup: Avoid unsterile makeup or facial products for at least 24 hours after the treatment.
  • Alcohol and Blood Thinners: Avoid consuming alcohol and taking blood-thinning medications or supplements (e.g., aspirin, ibuprofen, fish oil) for 24 hours before and after the treatment to reduce the risk of bruising and swelling.
Kiara Reju® Polynucleotides Pricing Guide:

Our treatment pricing is based on the treatment area being addressed. Kiara Reju® Polynucleotides treatments are performed by our medical doctors and are designed to support skin rejuvenation and improve overall skin quality in areas such as the under-eye area, face and neck.

Treatment Area: Cost:
Polynucleotides (Eye Area) R3,500 per treatment
Polynucleotides (Full Face) R5,500 per treatment
Polynucleotides (Full Face & Neck) R10,000 per treatment
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Before & after

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Meet our doctors

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FREQUENTLY ASKED QUESTIONS

Here are a few of the most common questions and answers regarding the use of Kiara Reju® Polynucleotides. If you have other questions or concerns about this treatment, please consult with one of our medical doctors.

Essentially, Polynucleotides is a refined pure gel created from salmon DNA derived from sperm. Salmon DNA has good compatibility with humans, which is why it was chosen as a good origin. 

Polynucleotides are an injectable bio-stimulator and a revolutionary anti-aging treatment. They use DNA chains derived from the nucleus of salmon or trout sperm cells to harness the bio-revitalizing powers of nucleotides. These injectables hydrate and rejuvenate the skin, providing a lasting glow and flawless complexion.

Nucleofill is the manufacturer and brand of Polynucleotides we make use of at our practices. Thanks to its polynucleotide-based bio-stimulation technique, Nucleofill is specially designed for skin renewal and bio-restructuring. It is bio-revitalizing and can be integrated into a mesotherapy protocol.

The new bio-restructuring gel of the Nucleofill range based on highly purified low molecular weight polynucleotides of natural origin, specifically created to improve the periocular area.

Several sessions of Nucleofill Polynucleotides are needed to fully benefit from this treatment. One session alone will not resolve all issues. Most patients require a course of 3-4 treatments, spaced two weeks apart.

Polynucleotides are long chains of nucleotides, which are the building blocks of DNA. They help with cellular repair and regeneration, moisturisation, and protection against harmful external agents such as UV rays.

The polynucleotide chains  attract and bind water molecules, allowing them to provide a strong moisturising effect, which can contribute to improved tissue elasticity.

Polynucleotides have a remarkable anti-free radical action. They counteract the skin damage which can accumulate due to various stressors, including cellular damage, stress, and exposure to UV rays, giving them a  protective and cell damage reduction role.

Polynucleotides creates an optimal environment for fibroblast growth, essential cells for tissue repair and regeneration.

Polynucleotides are derived from Salmon and can activate fibroblast and stem cells, enhancing the body’s natural capacity to regenerate skin cells.

This multi-faceted functioning classifies polynucleotides as regenerative treatments, offering a unique and innovative approach in the field of skin care and rejuvenation.

Typically, the effects of these treatments last 6 to 12 months. Regular treatments can provide more noticeable and long-lasting results.

Risks are usually minimal and may include temporary redness, or mild discomfort at the injection site. As these treatments use naturally derived substances, the risk of allergic reactions is significantly reduced.

  • Skin Regeneration: Polynucleotides stimulate cell growth and proliferation, enhancing collagen and elastin production, which are necessary for skin elasticity, firmness, and lift.
  • Wrinkle Reduction: They aid in reducing fine lines and wrinkles and improve skin texture and smoothness by promoting the formation of new skin cells and enhancing overall skin health.
  • Hydration: They exhibit hydrating properties and improve the skin’s ability to retain water, promoting healthier and more supple skin.
  • Anti-inflammatory Effect: They can soothe and calm skin, reducing redness, irritation, and inflammation caused by various skin conditions, including acne, eczema, hyperpigmentation, and rosacea.
  • Versatility: They are effective in treating loss of elasticity around the eyes, like crepey skin, under-eye darkness, and are also useful for treating dull and aged skin, as well as fine lines, subtle volume loss and wrinkles. 
  • Safety and Tolerance: Polynucleotides have an excellent safety record and are highly tolerated.
  • Quick and Lasting Results: Results can be seen as early as 20 days post-treatment, and the benefits have good longevity.
  • Cellular Turnover and Healing: They promote cell turnover, improve skin elasticity and hydration, and help heal sun-damaged skin. 

It can take up to 3-4 days for the product to fully settle. During this period, you might experience swelling, tenderness, redness, bruising, itching, or notice small lumps or bumps in the treated area. Initially, there may also be asymmetry due to uneven swelling or the way the product settles. Typically, these conditions self-correct as the swelling subsides and the product integrates with your tissue.

Yes, Nucleofill injections are safe for all skin types and are particularly beneficial for sensitive or sun-damaged skin.

Improvements in hydration and texture are noticeable within a few days, with enhanced elasticity and firmness becoming evident over the following weeks.

It’s recommended to wait 24 hours before applying makeup to allow the skin to recover fully.

Polynucleotides in Nucleofill neutralise free radicals, reducing oxidative damage and preventing premature ageing.

Nucleofill activates fibroblasts, the cells responsible for producing collagen and elastin, leading to improved skin structure and resilience.

For optimal results, treatments are typically recommended every 4–6 months.

Yes, Nucleofill is highly effective for repairing and rejuvenating sun-damaged skin.

Absolutely. Nucleofill is an excellent option for men looking to improve skin health and reduce signs of ageing.

Nucleofill provides deep, long-lasting hydration by binding water at a cellular level, which topical moisturisers cannot achieve.

Yes, by boosting hydration and collagen production, Nucleofill helps smooth fine lines and reduce wrinkles around the eyes.

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