Nucleofill Polynucleotides are a cutting-edge injectable treatment, offered by Natural Aesthetics, that is designed to rejuvenate and protect the skin around your eyes at a cellular level. Unlike traditional cosmetic procedures, Nucleofill focuses on improving skin health by using polynucleotides, naturally occurring molecules that deeply hydrate, repair, and enhance the skin’s natural regenerative processes. This innovative treatment is particularly effective around the eyes, where it helps restore vitality and reduce signs of ageing.
Nucleofill injections work by delivering a high concentration of polynucleotides directly into the skin in the periocular area. These molecules stimulate fibroblasts—the cells responsible for collagen and elastin production—resulting in improved skin elasticity and firmness. Additionally, Nucleofill enhances deep hydration by attracting and binding water molecules, ensuring long-lasting moisture. Its antioxidant properties combat oxidative stress, a key factor in premature ageing while promoting tissue regeneration for smoother, more youthful skin.
Polynucleotides are an injectable bio-stimulator and a revolutionary anti-aging treatment used to plump fine lines and wrinkles, address mild volume loss, and rejuvenate crepey or aged skin around the delicate eye area.
Performed by our medical doctors, each treatment involves a series of microinjections of Nucleofill Polynucleotides into the skin surrounding the eyes, also known as the periocular area.
The periocular area is an extremely delicate area. Constantly subjected to environmental pollution and constantly subject to movement when using facial expressions, the periocular area tends to age more rapidly than the rest of the face.
Nucleofill with highly purified polynucleotide matrix capable of activating the skin’s bio-regeneration processes both deep down (fat and bone tissue) and in the dermis (fibroblast stimulation).
Nucleofill determines three types of effects on the skin membrane (epidermis, dermis and subcutaneous tissue):
Nucleofill – the unique characteristics of an innovative product:
It can take up to 3-4 days for the product to fully settle. During this period, you might experience swelling, tenderness, redness, bruising, itching, or notice small lumps or bumps in the treated area. Initially, there may also be asymmetry due to uneven swelling or the way the product settles. Typically, these conditions self-correct as the swelling subsides and the product integrates with your tissue.
Nucleofill Polynucleotides | R2,500 per treatment |
Here are a few of the most common questions and answers regarding the use of Nucleofill Polynucleotides. If you have other questions or concerns about this treatment, please consult with one of our medical doctors.
Essentially, Polynucleotides is a refined pure gel created from salmon DNA derived from sperm. Salmon DNA has good compatibility with humans, which is why it was chosen as a good origin.
Polynucleotides are an injectable bio-stimulator and a revolutionary anti-aging treatment. They use DNA chains derived from the nucleus of salmon or trout sperm cells to harness the bio-revitalizing powers of nucleotides. These injectables hydrate and rejuvenate the skin, providing a lasting glow and flawless complexion.
Nucleofill is the manufacturer and brand of Polynucleotides we make use of at our practices. Thanks to its polynucleotide-based bio-stimulation technique, Nucleofill is specially designed for skin renewal and bio-restructuring. It is bio-revitalizing and can be integrated into a mesotherapy protocol.
The new bio-restructuring gel of the Nucleofill range based on highly purified low molecular weight polynucleotides of natural origin, specifically created to improve the periocular area.
Several sessions of Nucleofill Polynucleotides are needed to fully benefit from this treatment. One session alone will not resolve all issues. Most patients require a course of 3-4 treatments, spaced two weeks apart.
Polynucleotides are long chains of nucleotides, which are the building blocks of DNA. They help with cellular repair and regeneration, moisturisation, and protection against harmful external agents such as UV rays.
The polynucleotide chains attract and bind water molecules, allowing them to provide a strong moisturising effect, which can contribute to improved tissue elasticity.
Polynucleotides have a remarkable anti-free radical action. They counteract the skin damage which can accumulate due to various stressors, including cellular damage, stress, and exposure to UV rays, giving them a protective and cell damage reduction role.
Polynucleotides creates an optimal environment for fibroblast growth, essential cells for tissue repair and regeneration.
Polynucleotides are derived from Salmon and can activate fibroblast and stem cells, enhancing the body’s natural capacity to regenerate skin cells.
This multi-faceted functioning classifies polynucleotides as regenerative treatments, offering a unique and innovative approach in the field of skin care and rejuvenation.
Typically, the effects of these treatments last 6 to 12 months. Regular treatments can provide more noticeable and long-lasting results.
Risks are usually minimal and may include temporary redness, or mild discomfort at the injection site. As these treatments use naturally derived substances, the risk of allergic reactions is significantly reduced.
It can take up to 3-4 days for the product to fully settle. During this period, you might experience swelling, tenderness, redness, bruising, itching, or notice small lumps or bumps in the treated area. Initially, there may also be asymmetry due to uneven swelling or the way the product settles. Typically, these conditions self-correct as the swelling subsides and the product integrates with your tissue.
Yes, Nucleofill injections are safe for all skin types and are particularly beneficial for sensitive or sun-damaged skin.
Improvements in hydration and texture are noticeable within a few days, with enhanced elasticity and firmness becoming evident over the following weeks.
It’s recommended to wait 24 hours before applying makeup to allow the skin to recover fully.
Polynucleotides in Nucleofill neutralise free radicals, reducing oxidative damage and preventing premature ageing.
Nucleofill activates fibroblasts, the cells responsible for producing collagen and elastin, leading to improved skin structure and resilience.
For optimal results, treatments are typically recommended every 4–6 months.
Yes, Nucleofill is highly effective for repairing and rejuvenating sun-damaged skin.
Absolutely. Nucleofill is an excellent option for men looking to improve skin health and reduce signs of ageing.
Nucleofill provides deep, long-lasting hydration by binding water at a cellular level, which topical moisturisers cannot achieve.
Yes, by boosting hydration and collagen production, Nucleofill helps smooth fine lines and reduce wrinkles around the eyes.
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27 Willie van Schoor avenue, Tygervalley Chambers, Building 5, Ground Floor, Office 1
